Supplementary Material

File1 

Abstract

This systematic review examined differences in keystroke dynamics between individuals with mild cognitive impairment (MCI) and healthy aging people. A search of Embase, Medline, PsychInfo, PubMed, Web of Science, Google Scholar, and Cochrane Library from2012 to June 2023 identified 4,847 articles. After removing duplicates, 4,260 articles were screened based on abstract and title alone, resulting in 208 articles for assessing eligibility. Out of these 208 articles, five fully satisfied the inclusion and exclusion criteria of this study. Each showed the feasibility of pause-related keystroke dynamics to differentiate MCI fromhealthy aging aswell as conventional neuropsychological assessments. However, the optimal feature across keystroke dynamics could not be determined due to inconsistency in the analysis of the five studies. Future studies should employ receiver operating characteristic curve analysis with a variety of keystroke dynamics to determine if keystroke dynamics could be a potential surrogate for existing neuropsychological assessments.